The Program provides students with specific skills in space mission planning and in analysis and design of launchers, satellites, and remote metering/telemetry systems. It emphasizes systems-related and interdisciplinary aspects and is linked with research/innovation activities in European aerospace industries. Graduates will be able to address complex issues requiring analysis, development, simulation, and optimization in a wide range of aerospacerelated topics. The Master course is organized as follows. 1st year: knowledge is provided in major aerospace areas, Spaceflight Mechanics and Attitude Dynamics, Controls, Fluid Dynamics, and Propulsion (or telecommunications and remote sensing), Structures and Space Systems. 2nd year: students can four possible different curricula, namely, Space transportation, Spacecraft design and integration, Space missions and exploration, and Space payloads and applications for telecommunication, navigation, and Earth observation During the course the student work in team in hands-on projects and experimental activities related to realization of cubesats, rovers, small rockets, just to mention some of the options. Moreover, in their final thesis project the most skilled student can be involved in front-end research projects of current interest in aerospace engineering or in internships in companies. The master course is also tailored to preparing students to join a PhD program in aerospace engineering either at Sapienza or elsewhere.