SMA - Statistical Methods and Applications - is the acronym of the two-year international Master of Science entirely taught in English and delivered by the Department of Statistical Science (DSS). DSS is the largest Department of Statistics in Italy and its faculty members enjoy an international reputation in teaching and research. DSS hosts one of the most powerful computing resources at Sapienza University of Rome. Statistics is a data science which can open you to a world of opportunities. The Master program Statistical Methods and Applications provides students with specific statistical skills through a suitable mix of advanced data modeling methodologies and hand-on professional training to address complex scientific and socio-economic problems. The study plan can be flexibly geared to three main curricula: Data Analyst, Official Statistics, Quantitative economics. For all of them the Department has also identified European partners to allow access to a challenging double degree program. The Official Statistics curriculum is also released with the European Master in Official Statistics (EMOS) label awarded by the European Statistical System Committee (ESSC).